: Evaluation of SprayShield adhesion barrier system in a porcine model of gynecological surgery. Besides being biodegradable, they offer different … : Assessment of the effect on blood loss and transfusion requirements when adding a polyethylene glycol sealant to the anastomotic closure of aortic procedures: a case-control analysis of 102 patients undergoing Bentall procedures. : Role of biologic glue repair of proximal aortic dissection in the development of early and midterm redissection of the aortic root. Let’s talk about these substances and why they are used in implants. Surg. Acad. The book provides an up-to-date overview of the diverse medical applications of advanced polymers. : A reversible wet/dry adhesive inspired by mussels and geckos. It also prevents refracture occurring upon removal of a metal based implant, from the sudden transfer of load, previously borne by the implant, … Fertil. Aesthetic Plast. Assoc. Kuhbier, J.W., Reimers, K., Kasper, C., Allmeling, C., Hillmer, A., Menger, B., Vogt, P.M., Radtke, C.: First investigation of spider silk as a braided microsurgical suture. : Polyvinyl alcohol gel prevents adhesion re-formation after adhesiolysis in a rabbit model. The natural polymers were used by people for ages for heating, food, clothing, and in at that time medicine. Vorvolakos, K., Isayeva, I.S., Luu, H.-M.D., Patwardhan, D.V., Pollack, S.K. In addition, the Symposium offers recent perspec- tives on the critical problems of the material-tissue interface, the design criteria for silicone-based systems, and the varied … These are also known as water retention granules. Moreover, polymers have been often used regardless To repair, sustain and augment functions of organ. J. Prieto-Díaz-Chávez, E., Medina-Chávez, J.L., Ramírez-Barba, E.J., Trujillo-Hernández, B., Millán-Guerrero, R.O., Vásquez, C.: Reduction of peritoneal adhesion to polypropylene mesh with the application of fibrin glue. MAST Biosurgery from manufactures website. The metals that are used in orthopedic implants are stainless steel, cobalt-based alloys, and titanium. Thromb. J. Surg. Fertil. Natl. Res. FDA: Safety alert—INTERGEL adhesion prevention solution. Miyamoto, H., Futagawa, T., Wang, Z., Yamazaki, A., Morio, A., Sonobe, S., Izumi, H., Hosoda, Y., Hata, E.: Fibrin glue and bioabsorbable felt patch for intraoperative intractable air leaks. Ranger, W.R., Halpin, D., Sawhney, A.S., Lyman, M., LoCicero, J.: Pneumostasis of experimental air leaks with a new photopolymerized synthetic tissue sealant. Infect. Covidien AG (2008). CardioVasc. Dis. Int. Card. Holtz, G., Baker, E., Tsai, C.: Effect of thirty-two per cent dextran 70 on peritoneal adhesion formation and re-formation after lysis. Bonchek, L.I., Braunwald, N.S. Polymers and polymer based composites have gained increasingly larger applications in medicine and surgery. impacted the advancement of modern medicine. Lee, H., Dellatore, S.M., Miller, W.M., Messersmith, P.B. Gilbert, T.W., Badylak, S.F., Gusenoff, J., Beckman, E.J., Clower, D.M., Daly, P., Rubin, J.P.: Lysine-derived urethane surgical adhesive prevents seroma formation in a canine abdominoplasty model. Scand. Saez, C., Pardo, J., Gutierrez, E., Brito, M., et al. Firestone, D.E., Lauder, A.J. Surg. Allmeling, C., Jokuszies, A., Reimers, K., Kall, S., Vogt, P.M.: Use of spider silk fibres as an innovative material in a biocompatible artificial nerve coduit. Examples of pharmaceutical polymers and the principles of controlled drug delivery are outlined and applications of polymers for controlled drug delivery are described. One major problem in polymers is the slow, temperature-dependent, deformation it suffers under load, commonly called “creep“. Diamond, M.P., Burns, E.L., Accomando, B., Mian, S., Holmdahl, L.: Seprafilm® adhesion barrier: (2) a review of the clinical literature on intraabdominal use. Adhesive sealant biomaterials (2009). Oral. Today, the field of biodegradable materials and devices attracts polymer scientists and healthcare professionals in surgery, dentistry, pharmacology and regenerative medicine. Go ahead and login, it'll take only a minute. : Adhesions following cesarean delivery: a review of their occurrence, consequences and preventative management using adhesion barriers. Dove, J., Sheridan, P.: Adhesive protein from mussles: possibilities for dentistry, medicine and industry. Walgenbach, K.J., Bannasch, H., Kalthoff, S., Rubin, J.P.: Randomized, prospective study of TissuGlu® surgical adhesive in the management of wound drainage following abdominoplasty. The deposit obstructing the vessels can be broken down with a tiny spiral-shaped implant called a vessel support. 12/9/2018 29. Biodegradable implantable polymers for tissue engineering and drug release have the advantage to avoid a permanent and chronic immune response, and to avoid removal surgery; moreover the versatility of polymeric materials aloud the design of specific biodegradable … PAM is widely used as a soil conditioner. Uses of polymers in the field of medicine and surgery are increasing day by day. Shape memory polymers are another type with the ability to memorize their original shape. Biomater. Surg. Simo, K.A., Hanna, E.M., Imagawa, D.K., Iannitti, D.A. Man-made synthetic polymers are almost as manifold as the natural ones, although the most progress in development only started about in the Second World War. : An essential primer for understanding the role of topical hemostats, surgical sealants, and adhesives for maintaining hemostasis. Med. Cross-linked PAM is used absorb large quantities of water and release it over time. Cardiovasc. Polymers can bind the particles of a solid dosage form and also change the flow properties of a liquid dosage form. Steril. Artif. Jpn. Fibrinolysis. Mater. POL YMER IN MEDICINE AND SURGERY. Sci. Coselli, J.S., Bavaria, J.E., Fehrenbacher, J., Stowe, C.L., Macheers, S.K., Gundry, S.R. Ann. Frykman, E., Jacobsson, S., Widenfalk, B.: Fibrin sealant in prevention of flexor tendon adhesions: an experimental study in the rabbit. Am. Surg. Their injectability and shape memory performance allow them to be applied in bioprinting, minimally invasive surgery, and precision medicine. Res. Weinans, M.J., Kauer, F.M., Klompmaker, I.J., Wijma, J.: Transient liver function disturbances after the intraperitoneal use of 32 % dextran 70 as adhesion prophylaxis in infertility surgery. Biomater. Rose, B.: Safety of Hyskon for routine gynecologic surgery. Colorectal Dis. Neurosurgery. Polyglycolic acid polymer: Easy hydrolyzable by body fluid: Surgical applications, absorbable sutures implantable medical devices as anastomosis rings, plates, rods, pins, screws. Bull. Neurosci. Yoshioka, I., Saiki, Y., Sakuma, K., Iguchi, A., Moriya, T., Ikada, Y., Tabayashi, K.: Bioabsorbable gelatin sheets latticed with polyglycolic acid can eliminate pericardial adhesion. Mater. For example, nylon-6, 6, polyether’s etc. Fertil. J. Biomed. Dis. Intentional injuries include scission of skin to secure the operation area and resection of diseased tissues and organs, whereas accidental injuries can also occur presumably due to mechanical contact of devices and surgeon’s gloves with patient’s internal organs and tissues. Reconstr. APPLICATIONS: Science, Shazly, T.M., Baker, A.B., Naber, J.R., Bon, A., Van Vliet, K.J., Edelman, E.R. Nilsson, E., Björn, C., Sjöstrand, V., Lindgren, K., Münnich, M., Mattsby-Baltzer, I., Ivarsson, M.L., Olmarker, K., Mahlapuu, M.: A novel polypeptide derived from human lactoferrin in sodium hyaluronate prevents postsurgical adhesion formation in the rat. Polymers in medicine. Res. Biomater. Polymethylmethacrylate (pMMA) was one of the first polymers used as a biomedical material serving as a material to replace the human cornea when damaged3. Acad. Lyman, M.L., Sawhney, A.S.: Design of a synthetic pneumosealant. Properties: It biodegradable and decomposable. J. Thorac. Elvin, C.M., Vuocolo, T., Brownlee, A.G., Sando, L., Huson, M.G., Liyou, N.E., Stockwell, P.R., Lyons, R.E., Kim, M., Edwards, G.A., Johnson, G., McFarland, G.A., Ramshaw, J.A., Werkmeister, J.A. Thorac. : Prevention of postoperative peritoneal adhesions. Polymers are also used to Biotechnol. … Colon Rectum. J. Cardiothorac. Mater. The structure of polymers containing long and straight chains fall … Mater. Synthetic polymers are mainly homopolymers or copolymers of poly (α-hydroxyacid)s. The use of polymeric materials in medical devices and pharmaceutical applications has been extended in the last decades. Redl, H., Schlag, G., Dinges, H.P. Properties: Easy hydrolysable by body fluid. Mater. The Myomectomy Adhesion Multicenter Study Group: An expanded polytetrafluoroethylene barrier (Gore-Tex Surgical Membrane) reduces post-myomectomy adhesion formation. Reconstr. (eds.) Liakakos, T., Thomakos, N., Fine, P.M., Dervenis, C., Young, R.L. Iwasashi, M., Sakane, M., Saito, H., Taguchi, T., Tateishi, T., Ochiai, N.: In vivo evaluation of bonding ability and biocompatibility of a novel biodegradable glue consisting of tartaric acid derivative and human serum albumin. : A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (Duraseal Dural Sealant System) as a dural sealant in cranial surgery. J. Biomed. Lauto, A., Mawad, D., Foster, L.J.R. Materials which are not causing adverse effect on blood and other tissues can be used in diagnostic, surgical and can be implanted in the body. Otto Rohm is credited with the development of perhaps the most widely used polymer in orthopaedic surgery—poly(methylmethacrylate) (PMMA)—in 1901 [] but the material did not come into widespread use in orthopaedics until Sir John Charnley described its use for bonding prostheses to bone in the early 1960s [].A good review of the early work in characterizing PMMA including the evolution of the use in … Gynecol. These smart polymers can be used as cell/drug/protein carriers. B Appl. During surgery, tissue injuries occur intentionally and unintentionally. Surg. Gynecol. Electrosurgery not only … Polymers are the most important and largest family of materials being used in medical technology. Heart Valve Dis. Materials which are not causing adverse effect on blood and other tissues can be used in diagnostic, surgical and can be implanted in the body. Am. The biomaterials are the materials that can be implanted in body of living to provide special prosthetic functions or used as diagnostic, surgical and therapeutic applications. Fertil. J. Surg. : A rapidly resorbable hemostatic biomaterial based on dihydroxyacetone. These smart polymers can be used as cell/ drug/protein carriers. Classification of Polymers based on the Structure of the Monomer Chain. Biomacromolecules. A, Elvin, C.M., Danon, S.J., Brownlee, A.G., White, J.F., Hickey, M., Liyou, N.E., Edwards, G.A., Ramshaw, J.A., Werkmeister, J.A. Surg. J. : A randomized prospective multicenter trial of a novel vascular sealant. doi: Ennker, I.C., Ennker, J., Schoon, H.D., Rimpler, M., Hetzer, R.: Formaldehyde-free collagen glue in experimental lung gluing. Ann. Becker, J.M., Dayton, M.T., Fazio, V.W., Beck, D.E., Stryker, S.J., Wexner, S.D., Wolff, B.G., Roberts, P.L., Smith, L.E., Sweeney, S.A., Moore, M.: Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. Since then scientists in the medical field have turned biomedical polymers into a billion Grande, D.A., Pitman, M.I. Ann. Clin. Cheng, L., Lau, C.K., Parker, G.: Use of TissuePatch™ sealant film in the management of chyle leak in major neck surgery. Thorac. INTERCEED(TC7) Adhesion Barrier Study Group: Prevention of postsurgical adhesions by INTERCEED(TC7), an absorbable adhesion barrier: a prospective randomized multicenter clinical study. Mettler, L.: Effect of cross linked sodium hyaluronate in adhesion reduction within the gynecologic surgical window. Acta Chir. Natour, E., Suedkamp, M., Dapunt, O.E. J. Surg. Bae, S.H., Son, S.R., Kumar Sakar, S., Nguyen, T.H., Kim, S.W., Min, Y.K., Lee, B.T. Inst. Surg. J. Miyamoto, K., Masuda, K., Inoue, N., Okuma, M., Muehleman, C., An, H.S. Ann. : The use of adhesives in chodrocyte transplantation surgery: preliminary studies. It is usually used for local anesthetic and small surgery. Polymers have been mainly used to control the drug release rate from the formulations. Surg. Surg. Biomaterials. J. Thorac. Diamond, M.P., Kruger, M., Saed, G.M. Medical Devices Evidence Res. Ther. Poole, J.H. Glickman, M., Gheissari, A., Money, S., Martin, J., Ballard, J.L., CoSeal Multicenter Vascular Surgery Study Group: A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than gelfoam/thrombin: results of a randomized controlled trial. Synthetic biodegradable polymers, such as polyesters, polyanhydrides, polyorthoesters, polycarbonates, polyphosphoesters, polyphosphazenes, polyesteramides, polyalkylenoxalates, polyalkylcyanoacrylates, etc., are represented as materials which are being tested for use, or which have been already used in surgery, orthopaedics, and pharmacy. Surg. J. Such natural polymers like horn, hair, or cellulose have been utilized by human since beginning of manhood, and they have found application in medicine, e.g. J. Biomed. Eng. Ann. Biomat. Thorac. : Chemistry and mechanics of commonly used sutures and needles. Cha, H.J., Hwang, D.S., Lim, S.: Development of bioadhesives from marine mussels. Am. Eur. Res. Infect. Turmeric has been used as medicine for treating variety of internal disorders, including indigestion, throat infections, common colds up to cleanse wounds. Biocompatible and biostable polymers are extensively used to package implanted devices, with the main criteria that include gas permeability and water permeability of the packaging polymer to protect the electronic circuit of the device from moisture and ions inside the human body. Fertil. Shimada, Y., Hongo, M., Miyakoshi, N., Sugawara, T., Kasukawa, Y., Ando, S., Ishikawa, Y., Itoi, E.: Dural substitute with polyglycolic acid mesh and fibrin glue for dural repair: technical note and preliminary results. J. Ann. Biomater. Vasc. It is a versatile plastic that has been used in medical applications for over 50 years. 5. Janigen, B., Weis, C., Odermatt, E.K., Obermaier, R., Hopt, U.T. Colon Rectum. Find answer to specific questions by searching them here. Mater. Expert Opin. Thorac. Plast. Not logged in As a result, the implant can rub against surrounding tissue, leading to medical complications and possibly additional surgeries. Oncol. B Appl. (2003) Available from: Rice, V.M., Shanti, A., Moghissi, K.S., Leach, R.E. The field of controlled drug delivery is vast … It should be easy to fabricate, sterilize without alteration in properties, in short, and biocompatible. Res. Biomater. J. : Use of a modified chitosan-dextran gel to prevent peritoneal adhesions in a rat model. Carbohydr. J. Biomed. The … Polymers play a particularly an important role in modern medicine. Belg. Recent advances in prevention and management. : In vivo biodegradability and biocompatibility of porcine type I atelocollagen newly crosslinked by oxidized glycogen. : Expanded polytetrafluoroethylene (Gore-Tex Surgical Membrane) is superior to oxidized regenerated cellulose (Interceed TC7+) in preventing adhesions. Surg. : Evaluation of photo-crosslinked fibrinogen as a rapid and strong tissue adhesive. Allied Technol. : Effect of tisseel on expression of tissue plasminogen activator and plasminogen activator inhibitor-1. Res. J. Cardiothorac. J. Cardiothorac. Surg. Fertil. Neurosurgery. Minim. : Prospective clinical trial of SprayGel as a barrier to adhesion formation: an interim analysis. Polymers are used in everyday products such as disposable nappies Image courtesy of SCA Svenska Cellulosa Aktiebolaget; image source: Flickr. Surg. J. Nanomed. J. Lee, H., Lee, B.P., Messersmith, P.B. Polymers Used for Vascular Prostheses and Cardiopulmonary Bypass Surgery Polymers used for vascular prostheses or good blood flow include poly (ethylene terephthalate) fibers, expanded polytetrafluoroethylene foams, segmented porous polyurethanes, and microporous silicone rubber [9]. They can also be used to … Surg. USA. These smart polymers can be used as cell/ drug/protein carriers. J. Obstet. Medical uses for plastic materials include: Thin tubes called catheters are used to unblock blood vessels. Dig. Sawamura, Y., Asaoka, K., Terasaka, S., Tada, M., Uchida, T.: Evaluation of application techniques of fibrin sealant to prevent cerebrospinal fluid leakage: a new device for the application of aerosolized fibrin glue. Mater. Terasaka, S., Iwasaki, Y., Shinya, N., Uchida, T.: Fibrin glue and polyglycolic acid nonwoven fabric as a biocompatible dural substitute. Write a short note on polymers used in medicine and surgery. For this reasons, a lot of current research studies for medicine is focused on this group of materials. These high-performance plastics are also used in electrosurgery, a fast-growing medical field that includes forms of robotic surgery where electrical frequencies are used to destroy human tissue or make clean incisions. Lauto, A., Mawad, D., Barton, M., Gupta, A., Piller, S.C., Hook, J.: Photochemical tissue bonding with chitosan adhesive films. Surg. Minato, N., Katayama, Y., Yunoki, J., Kawasaki, H., Satou, H.: Hemostatic effectiveness of a new application method for fibrin glue, the “rub-and-spray method”, in emergency aortic surgery for acute aortic dissection. Synthetic and natural polymers (biopolymers) are commonly used in tissue engineering because of valuable properties eg. : In vivo study of wound bursting strength and compliance of topical skin adhesives. as suture material also for long time . J. Biomed. Synthetic biodegradable polymers, such as polyesters, polyanhydrides, polyorthoesters, polycarbonates, polyphosphoesters, polyphosphazenes, polyesteramides, polyalkylenoxalates, polyalkylcyanoacrylates, etc., are represented as materials which are being tested for use, or which have been already used in surgery, orthopaedics, and pharmacy. High polymers are used in medicine, surgery, or artificial organs in three ways: 1) to construct complete artificial replacements for human organs, 2) to repair, sustain, or augment function of normal organs, and 3) to provide a biochemical function. A. Suzuki, S., Ikada, Y.: Sealing effects of crosslinked gelatin. Hosp. Gynaecol. Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M., Leroux, N., Potestio, F., Rittenberg, D., Senikas, V., Soucy, R., Singh, S.: Society of obstetricians and gynaecologists of canada, adhesion prevention in gynaecological surgery. : Characterization of star adhesive sealants based on PEG/dextran hydrogels. Mettler, L., Audebert, A., Lehmann-Willenbrock, E., Jacobs, V.R., Schive, K.: New adhesion prevention concept in gynecological surgery. Biosci. polymers application on medical field 1. seminar presentation on polymers use in medical field presentation by (team-08) vivek kumar patel(1618987657) vishal kumar vishwakarma(1618987038) kapil singh(1618987681) abhineet kumar yadav(1618987682) suraj mourya(1618987656) 12/9/2018 submitted to mr. ab ullash sir 2. Breast Cancer (2012). Biomed. Mater. : Ionically cross-linked hyaluronic acid: wetting, lubrication, and viscoelasticity of a modified adhesion barrier gel. It surveys the applications of polymers to medical and surgical problems and contains discus­ sions on the biocompatibility of polymers, polymers as biomate­ rials, and the use of polymers in prosthetic devices and drug re­ lease systems. Fukunaga, S., Karck, M., Harringer, W., Cremer, J., Rhein, C., et al. The assistance of computer aided apparatus, the use of always more advanced instruments, the larger interest of the academic and industrial world, bring continuously new contributions to the research on biomedical and parmaceutical use of polymers. Eur. Cardiovasc. Haas, S.: The use of a surgical patch coated with human coagulation factors in surgical routine: a multicenter postauthorization surveillance. Properties: It is transparent and easy to mould. World J. Surg. In addition, the Symposium offers recent perspec­ tives on the critical problems of the material-tissue interface, the design criteria for silicone-based systems, and the varied … Establish project. : Review: adhesive biomaterials for tissue reconstruction. Res. Öllinger, R., Mihaljevic, A.L., Schuhmacher, C., Bektas, H., Vondran, F., Kleine, M., Sainz-Barriga, M., Weiss, S., Knebel, P., Pratschke, J., Troisi, R.I.: A multicentre, randomized clinical trial comparing the Veriset™ haemostatic patch with fibrin sealant for the management of bleeding during hepatic surgery. Fürst, W., Banerjee, A.: Release of glutaraldehyde from an albumin-glutaraldehyde tissue adhesive causes significant in vitro and in vivo toxicity. Spotnitz, W.D. Various polymers being used in conventional medical technology and surgery include Polyvinyl Chloride, Polyethylene, Polypropylene, Polystyrene, Polycarbonate, Acetal copolymers, Polybutylene terephthalate, Polyethylene terephthalate, a variety of Liquid crystal polymers and some specialised polymers … Mater. The book opens by presenting important background information on polymer chemistry and physicochemical characterization of polymers. Surg. B Appl. (Larchmt). You may also read Common Chemicals Used in Medicine. Am. Med. Interact. 1975 Edition by Richard Kronenthal (Editor) ISBN-13: 978-1468477467 Biomaterials. Weis, C., Odermatt, E.K., Kressler, J., Funke, Z., Wehner, T., Freytag, D.: Poly(vinyl alcohol) membrane for adhesion prevention. Sci. : The threat of adhesive embolization: BioGlue leaks through needle holes in aortic tissue and prosthetic grafts. 9. Steril. Surg. Polym. Fertil. Cardiovasc. : Evaluation of the potential anti-adhesion effect of the PVA/Gelatin membrane. Mayol, J.M., Zapata, C.: Gelatin-thrombin matrix for intraoperative hemostasis in abdomino-pelvic surgery: a systematic review. Synthetic polymers are mainly homopolymers or copolymers of poly(α-hydroxyacid)s. Natural polymers include proteins, such as collagen, gelatin, albumin and fibrin, and polysaccharides, such as hyaluronic acid, chitosan and chitin. Typical examples of natural biocidal polymers used in medicine are chitosan, poly-ɛ-lysine, gramicidin A, and host defense peptides (HDPs). Surg. Polymers are extensively used in regenerative medicine and tissue engineering due to their flexibility and versatile properties such as tailoring the damaged tissue's physical, chemical and mechanical properties by modification of functional groups during synthesis, according to the regeneration capability of tissues of the organs. Weis, C., Odermatt, E.: A-Part Gel—an efficient adheison prevention barrier. If all polymers and their medical applications are considered, there are at least hundreds of uses for medical plastics. A randomized controlled trial. Dent. Macromol. Fertil. Pharmacotherapy. Jt. : Polyphenolic substance of mytilus edulis: novel adhesive containing. J. Biomed. (2006). J. A, Horio, T., Ishihara, M., Fujita, M., Kishimoto, S., Kanatani, Y., Ishizuka, T., Nogami, Y., Nakamura, S., Tanaka, Y., Morimoto, Y., Maehara, T.: Effect of photocrosslinkable chitosan hydrogel and its sponges to stop bleeding in a rat liver injury model. Biomaterials, Takaoka, M., Nakamura, T., Sugai, H., Bentley, A.J., Nakajima, N., Fullwood, N.J., Yokoi, N., Hyon, S.H., Kinoshita, S.: Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. This book is an excellent guide to the recent advances … They can be sterilized easily and do not show … Hand. Lequaglie, C., Giudice, G., Marasco, R., Morte, A.D., Gallo, M.: Use of a sealant to prevent prolonged air leaks after lung resection: a prospective randomized study. Surg. J. Reprod. Today. Specifically, polymericbiomaterialsthatare biodegradable provide the signifi-cant advantage of being able to be broken down and removed af-ter they have served their function. This category has the following classifications: Linear Polymers. Young, P., Johns, A., Templeman, C., Witz, C., Webster, B., Ferland, R., Diamond, M.P., Block, K., diZerega, G.: Reduction of postoperative adhesions after laparoscopic gynecological surgery with Oxiplex/AP Gel: a pilot study. Surg. OJOG. Montorsi, M., Zerbi, A., Bassi, C., Capussotti, L., Coppola, R., Sacchi, M.: Italian Tachosil Study Group, Efficacy of an absorbable fibrin sealant patch (TachoSil) after distal pancreatectomy: a multicenter, randomized, controlled trial. J. Biomed. Johns, D.B., Keyport, G.M., Hoehler, F., diZerega, G.S. … Fazio, V.W., Cohen, Z., Fleshman, J.W., van Goor, H., Bauer, J.J., Wolff, B.G., Corman, M., Beart Jr, R.W., Wexner, S.D., Becker, J.M., Monson, J.R., Kaufman, H.S., Beck, D.E., Bailey, H.R., Ludwig, K.A., Stamos, M.J., Darzi, A., Bleday, R., Dorazio, R., Madoff, R.D., Smith, L.E., Gearhart, S., Lillemoe, K., Gohl, J.: Reduction in adhesive small-bowel obstruction by Seprafilm adhesion barrier after intestinal resection. Cardiovasc. Gynecol. It surveys the applications of polymers to medical and surgical problems and contains discus­ sions on the biocompatibility of polymers, polymers as biomate­ rials, and the use of polymers in prosthetic devices and drug re­ lease systems. Res. J. Gynecol. Steril. Petter-Puchner, A.H., Walder, N., Redl, H., Schwab, R., Ohlinger, W., Gruber-Blum, S., Fortelny, R.H.: Fibrin sealant (Tissucol) enhances tissue integration of condensed polytetrafluoroethylene meshes and reduces early adhesion formation in experimental intraabdominal peritoneal onlay mesh repair. : Dissected aortic sinuses repaired with gelatin-resorcin-formaldehyde (GRF) glue are not stable on follow up. Ann. Abstract and Figures Multiple biological, synthetic and hybrid polymers are used for multiple medical applications. Are commonly used sutures and implants contact with blood and tissues should not cause any harm or destroy of. 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